Effects of histamine aerosol in byssinotic subjects.
نویسندگان
چکیده
The changes in symptoms and lung function tests of 26 cotton cardroom workers were investigated before and after inhalation of histamine aerosols. Three subjects with no chest symptoms and ii with uncomplicated byssinosis showed no evidence of any pulmonary reaction, but I2 bronchitic byssinotic subjects showed evidence of the pulmonary hypersensitivity found in patients with chronic bronchitis alone. These findings cast doubt on the possible role of non-antigenic histamine liberators in the mechanism of production of 'return-to-work' tightness in byssinosis.
منابع مشابه
Role of histamine in the aetiology of byssinosis. I Blood histamine concentrations in workers exposed to cotton and flax dusts.
The formation or the accumulation, or both, of histamine in the lungs may be potentiated by agent(s) present in cotton dust at higher level(s) than in flax dust and negligible in cottonseed dust. It has been suggested that such potentiation may be due to the activation of the ability of the lung to produce histamine and/or produce or recruit mast cells; this may present an acceptable explanatio...
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عنوان ژورنال:
- British journal of industrial medicine
دوره 24 1 شماره
صفحات -
تاریخ انتشار 1967